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The pharmacy of the future? Personalized pills, 3D printed at home | Daniel Kraft

1965 ratings | 77336 views
We need to change how we prescribe drugs, says physician Daniel Kraft: too often, medications are dosed incorrectly, cause toxic side effects or just don't work. In a talk and concept demo, Kraft shares his vision for a future of personalized medication, unveiling a prototype 3D printer that could design pills that adapt to our individual needs. Check out more TED Talks: http://www.ted.com The TED Talks channel features the best talks and performances from the TED Conference, where the world's leading thinkers and doers give the talk of their lives in 18 minutes (or less). Look for talks on Technology, Entertainment and Design -- plus science, business, global issues, the arts and more. Follow TED on Twitter: http://www.twitter.com/TEDTalks Like TED on Facebook: https://www.facebook.com/TED Subscribe to our channel: https://www.youtube.com/TED
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Text Comments (188)
Stimulants i like (5 days ago)
so how do i get the pervitin
T Com (1 month ago)
That’s awesome let’s stop talking about it and do it
Cecilia Spears (1 month ago)
That was awesome! I hope this becomes actualized!
Abdul Rauf Saleem (2 months ago)
Size of the pill will increase by integrating the drugs in one pill?
Abdul Rauf Saleem (2 months ago)
If increased then there will be difficulty in swallowing
Matt G (2 months ago)
Thanks Dr. Mario
Edmund Singleton (2 months ago)
Your doctor prescribes some lifesaving medications, you take to your local pharmacy to have filled, there is no way for you to know if you have been cheated with an outdated ineffective generic or a lower dosage, its not like you have a home lab to first test them, so you ingest the medications as prescribed by an highly educated doctor without expecting any errors, hoping that the pharmacist like the prescribing physician is a trusted drug pusher, not like one found on the street, has  scruples, is not blinded by pure profit, nice to take under consideration, hoping for the best before dying…You now realize in trust we trust our all…including life, limbs and pocket book contents too…
Cảm ơn rất nhiều, video nói về xu hướng rất hay. Sinh viên dược sĩ đại học 40 Trần Cung của trường cao đẳng dược Hà Nội hãy đón xem video này nhé
BeaglesGuy (2 months ago)
THANK YOU! I have been telling people for the last ~2 years that the next major generation of 3D printers will be used for personalized medications. I only ever get disbelief or ridicule in return.
Leocram Vinci (3 months ago)
I think you just take too many pills...
Mr. X (3 months ago)
Laura Magas (3 months ago)
It's an interesting perspective and very futuristic and convenient; however, concerning also
Raiden X flare (3 months ago)
You guys know Dr sebi?
Kay Realist (3 months ago)
Someone please wipe the mans side of his mouth. He is foaming at the mouth. -_-
sdrawkcabgnipytmi (3 months ago)
"That are delivered by drone" Nope, this guy isn't selling hype or anything...
TheMightyGumball (4 months ago)
Sounds interesting and fun but maybe focus more on eliminating the need for pills before focusing on making it easier for people to get them?
Raul Archie (4 months ago)
This cuck doesn’t care about lives. Him and big pharma only want more drugs in the streets. This solution is almost similar to when car companies create hybrids. It doesn’t solve anything it just adds to the problem. They could care less about pollution or the opioids crisis
Swae Ocean (4 months ago)
The future? Like, dudes.... we in the underground have been creating our own chems at home for decades. The suits are so lame.
Kimberley O'Connell (4 months ago)
I’m impressed I hate taking meds I don’t need. This is definitely something that needs to be considered by doctors and the government since they persist on telling people what meds to take and can’t figure out how to handle the medical problems in this country.
Legitness (4 months ago)
To little information. I'm not buying anything!
Asdfghjkl (4 months ago)
What a wide stance
Open School (4 months ago)
Simply mind-blowing. Still, we have to wait and see how it evolves.
fernando silva (4 months ago)
vai brasil.
Kalista Renee (4 months ago)
starting w nursing homes incase it doesnt work out .. i see what they did there
Amin Asnaei (4 months ago)
WOW , Wisdom ....... nice job .
phin thayphaly (4 months ago)
thank you
Josh Campbell (4 months ago)
10:40 - Mom these sprinkles taste horrible. NO!
dennis (4 months ago)
no 1 english learning show
Holly Hruska (4 months ago)
I have been tormented over what I know. American medical school is a laughing stock. Fly my butt to Switzerland.
Eliot Mitzéus (4 months ago)
If it was that easy, that you could simply put the moleculestogehter like LEGO bricks, then there would be no problem developing litterally anything in this world, but thats not the matter at the moment right? Get a grip please, this is bullcrap ;)
DeathAngel (4 months ago)
i like what he's saying, but i think giving the public access to print pills in their own home, unsupervised, would be a huge health risk/mistake.
ALFA (4 months ago)
we will be more healthy if we can print our own damn money.
Zahlenteufel1 (4 months ago)
Not really 3D printing this is basically the glorified version of that raspberry pi smart bartender.
Little Jonathorn (4 months ago)
Yes!! All for it. As a person who has to take about 10 pills on a daily basis. Yes.
Animesh Sharma (4 months ago)
Killer App, literally...
Stephanie Taylor (4 months ago)
These is neat but how does this affect cost of pharmaceuticals in the future. The cost of prescription is a huge concerning factor in the United States and other parts of the world.
Jaded Cynic (4 months ago)
You dont have to preach to me about health. I eat one highly nutricious meal every day. 3 meals a day is not needed, except of course to support a bloated food industry.
Leonora Dompor (4 months ago)
I take Biperiden as needed only not main medication
Leonora Dompor (4 months ago)
I have 2 main medications lifetime Haldol and Seroquel and healthy diet eating fruits and vegetables drinking fresh vegefruit juices and i am very healthy and very functional. I am not diabetic and not high blood and not obese
Zoophilia Consultant (4 months ago)
He is actually AI in disguise trying to rule the world!
ki daniels (4 months ago)
The problem with compounded medications is meds are compounded without full knowledge or consent based on any Dr prescribing meds they see fit under the auspices of the advancement of medications and off label usage of medications. Case in point the use off antipsychotics to treat what often amounts to misdiagnosis and or medication trials. Let's speak of genomics you mentioned...there are meds that target genes meaning that you maybe targeted via your genes to your demise. Your theories are great when posed in a pawsitive light how there is a dark side to medications and posing only one side of the sword still creates a lethal combination. Mandated medications are a reality...what protective measures shall be instituted to assure that we in fact are not becoming fodder for a dangerous and potentially lethal situation that in fact shall and does create a lethal dependence across the board regardless of wether it is pain meds or high blood pressure. Safety issues are inherent in the practice of medicine world wide and until we address this with specificity I am less likely to surrender my life 4 someone else's potential misjudgment and human error.
Fernando Zigunov (4 months ago)
1:35 Speaks about his own grandfather's death as if it's nothing?
JessyinCoolbeanie (4 months ago)
Japan already have that machine that makes the right dosage for the right person... but still pharmacists should handle it since they know how a medicine works, people can’t just have medicine maker at home... and one thing, there are some substance or medicines that would react to each other.. the kind of idea has risks, so we can’t just mix different medicines or vitamins to one tablet or capsule.. hope that in the future, professionals are still helpful than a machine alone.
JessyinCoolbeanie (3 months ago)
+Nanoha Fate would agree to that, but the pharmacists still needs to have control over the machine... it's not easy to display all medicine ingredients in one machine standing by at home without even a professional's handle, there are ingredients that have conditions for it to be stable, like temperature for example. There's even a lot of process to make one tablet, and a machine alone can't fulfil it without the professional's work. The making of tablets isn't just mixing powders and compress, there are still many process to activate a certain component for the med to be effective and safe to be taken. I would agree for a dispensing machine that gives a whole packed med and needing a doctor's prescription, but not to personalising med, it's just too risky.
Nanoha Fate (3 months ago)
simply way to solve it is lock the machine and have it require doctors prescription to unload drugs doctors can have special accounts which they use to send prescription digitally to machines which are at patients home
kebakent (4 months ago)
Based on my experience with the automated espresso machine at work giving random dosages of milk powder, and the tendency of my fast food milkshakes to taste like whatever the last person ordered, I'm a bit skeptical of such a device.
Cindy Prisilia (4 months ago)
This is not as simple as it serves to you. What about drugs interactions? contraindications? Not all drugs can be combined tho. Many things need to consider even to make 1 pill
Shannon Weston (4 months ago)
There are a lot of people in the comments talking about living a healthy lifestyle to prevent needing meds. I wonder how healthy living prevents being born with a heart that is too big for your body or any other congenital heart defect like my mother, with type 1 diabetes like a best friend of mine, with immune system disorders or psychiatric conditions like Bipolar or Schizophrenia. There are things eating kale and running 10 miles can't cure. Medicine and science isn't the enemy. Big phrama is bad, yeah got it, but swinging back to the dark ages where we treat science like witchcraft and pseudo-science like the gospel isn't the way to go either.
BeaglesGuy (2 months ago)
Thea Robertson (4 months ago)
Hear hear! I can't think of a better way to put it.
tarns22 (4 months ago)
I agree.  Being born with a congenital birth defect, I need my prescribed medicines to survive.  If I don't take them...I die (a slow, horrible death as the effects of not taking these meds takes over my body), simple as that.  When I was a young adult, I rebelled against my meds and tried not taking them for a little while - this led me into a very dangerous place, health/life-wise - I risked my life. Lesson learnt, the very hard way. Yes, I live as healthy a lifestyle as I can, to help prolong my life, and the quality of it, and this body & mind I live in, as long as I possibly can (of which, my lifespan will be shorter than average) - but, the fact is, these medicines are also prolonging/saving my life.
J. P. (4 months ago)
Glad to see that Cameron from Ferris Bueller's Day Off has succeeded.
Keith Cooper (4 months ago)
Amazing new technology!
Sumana S Kumar (4 months ago)
This was a good one but i feel eating well and exercising regularly will keep everything well.
Ryan B (4 months ago)
Yay so now we can breach the privacy and security of everybody even more. We'll know if you're exercising, using drugs, having a one night stand, eating junk food all for the price of what everybody should have which is a good healthcare system. Nothing will stop these machines from sharing your confidential information. You'll have the Big Brother NSA and CIA, Big Pharma and the Hacker guy down at the park dropping in. You started selling our privacy and security long ago and now you want to start selling our bodies too. Good Job.
ren lin (4 months ago)
Don't let your kids touch that device...
antanoh (4 months ago)
I love when a doctor tries to revolutionize pharmaceuticals, without even consulting a pharmacist
Alpha Strength (4 months ago)
Are printed teachers the future of school
I really hope this is not the pharmacy of the future. This is just a better way to sell drugs: bringing the big pharma straight into your kitchen. Maybe we try not to get sick first? We could easily avoid half of the modern sickness just by having a healthier lifestyle.
william smith (4 months ago)
Half though. Still some outside stuff is needed
boson96 (4 months ago)
I love this so much!! Feels like science fiction. Singularity 2050 baby!!
Ingenium (4 months ago)
Finally a really interesting talk on talk again 👍
Gamma Light (4 months ago)
Morticia147 (4 months ago)
Basically a good idea, but in real life it's just another way for Big Pharma to sell their crap. So sad that all that brainforce goes into the pharma industry and not into unterstanding the body chemistry and make it heal it self. There are situations where modern drugs are good and helpfull and that's in emergency situations. Their would be a good use for this technology but then, their is no time for this.
Why outsource to a 3D printer, when our body can naturally produce the hormones as when required. n
This is really a PILL Industry ( Permanent Investment to Loose Life). My father died of these pills! Got liver transplant, got heart bypass, and finally died of multi organ failure, just at the age of 66! These people are so eager to get the bodies dissected, as that builds up their business! It's better to build technologies to stay safe from these pills! These are just an add on to our unaware journey of suppression (which is not life), as we have got ourselves so much furnished with the trait of instant cure!
Amanda Anderson (4 months ago)
William Stanley (4 months ago)
JESUS told his disciples with man this is impossible but with God all things are possible.
William Stanley (4 months ago)
It's only the things we do for JESUS that will survive the way of eternal life.
boson96 (4 months ago)
Tyler Smith (4 months ago)
TED - If everyone’s with a smart phone these days. People without them should be widely valued in a sense. Transmitting the germs from the smart phone revolution. Used to have to change the clocks, clean key boards at school or library. Now I’m just depressed
C L (4 months ago)
I was just thinking today that I wish I wasn’t the one telling my doctor what antidepressants to give me. I want my doctor to be able to test my brain to figure out what exactly my body needs to be happy.
Anon archist (4 months ago)
Where would I get the filament/substrate to print my meds, perscribed by a doctor through a pharmacy? Great, I save the pharmaceutical company the money of having to turn their raw chemicals into pills which they will pass the savings on to themselves, AND I get the expense and hassle of buying and operating my own pill printer! I could buy a pill press and use a compounding pharmacy right now if I were dumb enough to want this.
Catandthefunk (4 months ago)
I don’t think we should let folks produce their own drugs
Adnan A (4 months ago)
I wonder how long practical, widespread use will take to be implemented.
Jaded Cynic (4 months ago)
In the future medical problems will be fixed using the bodies own systems without any drugs. Assuming we break big Pharmas fraudulent hold on civilization.
Andrew Polk (4 months ago)
Jaded Cynic It is certainly true that diet and exercise cannot cure everything (I never claimed such a thing). However, it is a very effective method of non-pharmacologic management for many diseases like hypertension, heart disease, obesity, diabetes, depression, and the list goes on...
Jaded Cynic (4 months ago)
+Andrew Polk diet and excercise do not fix injuries...genetic problems or disease. Your view is much to simple.
Andrew Polk (4 months ago)
Jaded Cynic believe it or not this kind of technology is available today! In the medical community we refer to it as diet and exercise 😉
David A (4 months ago)
Coming Soon to a Drug Dealer near you!!!! The Perfect Cocktail!!! Lol
Becca (4 months ago)
I cant believe im watching this. I was thinking of the same idea but in a vitamin form. Spooky
lateblossom (4 months ago)
This is a neat idea, but I see a lot of issues to be worked out, and a black market as well.
JY Lin (4 months ago)
The title 3D printing is probably inappropriate since that machine is simply a more advanced dispenser.
Pwn Network (3 months ago)
he printed the pill, so it is a 3d printer for pills at least
Josh Campbell (4 months ago)
Through a synergistic disruptor approach, this Pharmaceutica game changer has laid out a roadmap to capture the low-hanging fruit in today's medical market. Doing good like a boss with more 3D printing and augmented virtual reality than ever. You've got this! 🙄 But really, cool tech, lots on the horizon in the medical field. Let's hope we get to see a lot of it in our lifetime.
Robert Neve (4 months ago)
but buzz words. You need hip buzz words
big chungus (4 months ago)
I think it's pretty accurate
Hajdone (4 months ago)
This guy talks for 3 minutes and feels like 30
Elmeromero (4 months ago)
Great concept, idea, prototype but when can we start dumping money into getting away from big pharma man wtf.
FSK1138 (4 months ago)
9:00 one giant pill.. .. .. or suppository . ..(o_0)
emi (4 months ago)
Oooh this is a no no. Overdose, mixing drugs that have bad reactions with one another..
Eric Nguyen (4 months ago)
Software would restrict that I doubt that anyone would let that lawsuit occur.
Isabelle Elliot (4 months ago)
Abilify that high on the list? Wow
Mihir Patel (4 months ago)
question ade (4 months ago)
Is this an advert? It sure sounds like one
Isabelle Ngo (4 months ago)
What about drug interactions though? There are many drugs you can’t take together.
BeaglesGuy (2 months ago)
+Javin Avoiding contraindicated medications doesn't work for many people in today's world. I'm elderly and on disability and must get my medications through the most inexpensive means, and drug prices vary widely between pharmacies. So I have to deal with my primary care provider and specialists (cardiologist, endocrinologist, nephrologist, urologist, etc.) and getting medications via Costco, mail order, my local pharmacy, Walmart, etc. Different systems; different software. For every medication change, I must force whichever provider I'm with at that appointment to review my entire current list of medications and doses and hope they know of any potential problems. A few trips to the emergency room and urgent care tells me this just doesn't work.
ismael horan (4 months ago)
Isabelle Ngo that is right
Robert Neve (4 months ago)
As said you'd make sure the printer wouldn't create such combinations but I would also hope those drugs wouldn't be in the printer together. You could only have basic drugs in there at home anyway.
Javin (4 months ago)
Software already does this in healthcare today. It prevents them from giving out medications based on allergies and medication conflicts based on prompts in the software. The same thing could be applied here.
Genhen (4 months ago)
the software would stop you from taking anything that is bad together. Just enter it once, and nobody will ever make that mistake again
69LiamO (4 months ago)
I can't imagine selling large quantities of APIs to the public is going to be smiled upon by the FDA and other global regulatory bodies. It's a nice idea but implementation and approval will be difficult.
Fizzy (4 months ago)
As a pharmacy student, I don't even know where to begin with the problems this thing could cause and all the exceptions we would have to make.
David Gault (4 months ago)
Scarlet Matt (4 months ago)
Disruptive technology. But with this, security should be a priority. We don't want someone tampering with the printer and making an overdose capsule of blood thinners or similar.
John C (4 months ago)
dispense more drugs instead addressing the problem. THE AMERICAN DIET WITH A SIDE ORDER OF LAZINESS.
Eric Nguyen (4 months ago)
Um antiviral meds? Antibiotics? You should me more worried about the dangers of having the chemical compounds in the filament accessible to the public.
rb93077039 (4 months ago)
The potential for expediting suicide is my first concern, because those desperate enough will bypass any safeguards.
erdiaz13 (4 months ago)
Your picture is hilarious!
Virtual IT Boy (4 months ago)
This is really the future ! :) This will be so much better.
J3m51mct (4 months ago)
Placebo effect 🤔🤔🤔 “t b nk cells”????
Wake Up (4 months ago)
3D printed coca! The end of doubt😎
11cylynt11 (4 months ago)
Awesome, so how would one print an LSD pill at home?
shadfurman (3 months ago)
Decriminalization is the future. The DEA violates the 9th and 10th amendments. Black markets increase violent crime since they don't have access to courts for dispute resolution. Putting people in jail for non-violent crimes reduces the income potential of households and increases poverty, which increase the burden on tax payers by requiring more welfare, the costs of incarceration, the costs of increased police to reduce violent crime.
Raiden X flare (3 months ago)
Domenic Paga (4 months ago)
In your bathtub,bro.
Beyond Cinema (4 months ago)
try shrooms dude :) the beauty of trip is in its novelity once we customize it, it becomes another random drug
Miko Miko No Mi (4 months ago)
not niga, not at all
Tony Ray (4 months ago)
"What if",... doctors stop taking bribes and putting their Financial Status above the quality of Health Care they provide? What if doctors decided to start actually using real medicine instead of trying to make their yearly bonus? It seems as though they'll try anything and everything except going back to natural medicine. It was natural medicine that cured my autoimmune deficiency disorder, and proved every diagnosis absolutely wrong that they've ever put on me. Take money out of the equation and you'll start seeing people get healed.
Cybersquirrell (4 months ago)
+Andrew Polk Just wanted to say that was probably one of the best responses I've ever seen. Also, I'd like to add that purely anecdotal accounts doesn't constitute as evidence when talking about anything. Just because it worked for you doesn't mean it is the perfect solution.
Andrew Polk (4 months ago)
Tony Ray First of all, they may sound similar, but autoimmune disorders and immune deficiency disorders are very different concepts. Second, I don’t think it is fair to say that all doctors are inherently opposed to ‘natural’ medicine. Actually, many modern medications are derived from sources in nature. Some common meds like insulin and levothyroxine are even produced by our own bodies. Most good doctors would at least consider prescribing a ‘natural’ medication that was proven both effective and safe. The truth is that many prototypical ‘natural’ remedies have either been proven to be ineffective, or there is simply not enough scientific evidence available for doctors to recommend for or against them. In fact, clinical recommendations and practices change every day based on the emergence of new evidence regarding the safety and efficacy (or lack thereof) of new and existing treatment options, including natural ones.
Rafi (4 months ago)
So much psuedoscientists in the comments here..
Xeno Phon (4 months ago)
Why do doctors and medical researchers always ignore a very important factor to all they propose? Trust. Many, for good reason, do not trust what you say or ask us to do anymore because too often the motivations of the various medical fields have found to be financial, not any real drive to help anything. It may not be the average doctor that is this way, but top beats bottom. /watch?v=WFnspLpRA3Y&t=0s&list=WL&index=37
Mustafa Can Güngör (4 months ago)
jackie chan knows his medicine
Mustafa Can Güngör (4 months ago)
John Vatic (4 months ago)
Come Oooon!
Pawan Gupta (4 months ago)
Maite V. F. (4 months ago)
My grandparents ate a normal Mediterranean/Spanish diet, the only thing they did was clove of garlic in the morning with hot water and empty stomach, small glass of red wine during lunch time, coffee, a tiny piece of pure black chocolate daily, pure real honey, herbs, extra virgin oil, stews and broths with spanish cured ham bones, and everything bought in REAL markets (with stands and so on) from the land, farms, sea to the table. They died of old age, never took pills, only when they were very old... Same with my friends' grandparents...
Fizzy (4 months ago)
Your grandparents had great genes then, good for them!
Hi ( ͡° ͜ʖ ͡°)
Rr Ii (4 months ago)
Yeah, but can it roll me a fatty.?
blue_tetris (4 months ago)
The pharma industry is one of the biggest lobbies in the US, paying out to sitting Congress members along with the oil, defense, gun, and telecomm industries. They'll do anything to prevent insurance and health care reform, including lifting regs that allow consumers to self-diagnose. The Executive has completed regulatory control, by appointing foxes to guard every separate hen house we've tried to construct, removing even more agency from the consumer and the people whom the government is meant to represent and protect. This pipe dream is a long way off. Americans claim to want money out of politics, but their votes consistently speak otherwise; they will get sicker and sicker as a result. Cool tech, though. As usual, our technology far exceeds the political will of those whose lives it could save.
DzaMiQ (2 months ago)
Couldnt said it better.
Raul Archie (4 months ago)
Thank you. So much truth. Thank you!!! Finally someone said it.
Spencer Freed (4 months ago)
Money in politics is only possible because of politics in money. In other words, the real solution to your predicament is to remove the governments hand out of medicine so that lobbyist won't have power.
Robert Neve (4 months ago)
+annoloki then don't buy their drugs. Oh wait you don't have a choice because they developed them. You don't seem to understand basic economics. New companies run up debt to make a product. They then have to pay off that debt when they sell that product. They also need to keep up r&d or they stop being number 1. Drug patents are short and generic makers are always willing to decimate the big companies cash cows. If they don't keep up r&d they will eventually get over taken and die
annoloki (4 months ago)
"Without the extra revenues they won't be able to spend so much on R&D" -- this is only true in the imaginary world that badly educated economists without real-world knowledge like to guess about... the reality is that drug company revenue is NOT a predictor of their R&D spend, and more often you actually see the exact opposite result than what you think... that as they make more money, the amount they spend on R&D goes down, as a proportion of the total, and often even in absolute amounts. For example, among the top 4 largest drug companies in the US, the largest by revenue is the lowest R&D spender, with each of the next three spending more than it's larger competitors... presumably because the #2 company wants to be #1, whereas #1 will spend as little as possible to try maintain its position. Spending less on R&D increases short term profits, and near-term profits are more valuable than distant-future profits. Secondly, you'd be surprised how much R&D is publicly funded, either directly as research (eg, in universities and research institutions) or indirectly through tax-inversion schemes (when IP is moved to an over-seas subsidiary which then licenses it back at a large fee, allowing the drug or technology to make a fake loss to get a tax rebate). Simple economic models based on how things "should" work are not things you should use to understand how things actually operate when the cheapest way to make the most profit is to run attack ads against anyone running for office who isn't sufficiently "friendly" to you. Buying politicians is too profitable an investment for any large industry to ignore.

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